Can you take Lion's Mane and Ashwagandha together?

Many people do, often Lion's Mane in the morning and Ashwagandha in the evening. Check with your GP first if you are pregnant, breastfeeding or taking medication.

Is Lion's Mane or Ashwagandha better for stress?

Neither has an authorised UK health claim for stress. Magnesium and Vitamin B6 contribute to normal psychological function.

When should I take Ashwagandha?

Most people take it in the evening. Follow the label on your product.

Comparison · Last updated 7 October 2026

Lion's Mane vs Ashwagandha: which one, and can you take both?

Should I take Lion's Mane or Ashwagandha?

The short answer

Lion's Mane is a mushroom, traditionally used in East Asia and usually taken in the morning as part of a daytime routine. Ashwagandha is a root from the Ayurvedic tradition, and most people take it in the evening to wind down. Neither has an authorised health claim in the UK, so neither can promise focus or calm. They are often taken together, one in the morning and one at night. If you want an approved claim, look at the vitamins and minerals alongside them: Vitamin B12 contributes to normal psychological function, and Magnesium and Vitamin B6 to normal psychological function and the reduction of tiredness and fatigue.

Lion's Mane vs Ashwagandha

Lion's Mane vs Ashwagandha
	Lion's Mane	Ashwagandha
What it is	Mushroom (Hericium erinaceus)	Root (Withania somnifera)
Tradition	East Asian culinary and traditional use	Ayurveda
When people take it	Morning, with breakfast	Evening, or split morning and night
Caffeine	None	None
Approved UK health claim	None	None
Who should avoid it	Anyone with a mushroom allergy; check with your GP if on medication	Pregnancy, breastfeeding, thyroid conditions; check with your GP if on medication
Our product	FOCUS capsules, powder, gummies, drink	RELAX capsules (with Maitake, L-Theanine, Magnesium, B6)

Pick by your day

Pick by your day
	Try this
You want a daytime habit	Lion's Mane in the morning
You want an evening wind-down ritual	Ashwagandha in the evening
You want both	FOCUS in the morning, RELAX in the evening

The trade-offs

Lion's Mane (Grass & Co. FOCUS)

Fruiting body with published batch certificates
Paired with Vitamin B12, which has an approved claim
Four formats

Lion's Mane itself has no authorised health claim
Contains ginseng in the capsules, not for pregnancy or some medication

Ashwagandha (Grass & Co. RELAX)

Paired with Magnesium and B6, which have approved claims
One or two capsules a day

150mg Ashwagandha root powder, lower than many single-ingredient products
Not suitable in pregnancy or with thyroid conditions

The verdict

They are not rivals. Lion's Mane fits the start of the day, Ashwagandha the end of it. Choose by when you want the ritual, or use both.

Where Grass & Co. loses

If you want a high-dose, single-ingredient Ashwagandha, ours is not it: RELAX uses 150mg of root powder as one part of a blend. A dedicated Ashwagandha extract will give you more of it for less money.

Mentioned in this piece

Questions people ask

Can you take Lion's Mane and Ashwagandha together?: Many people do, often Lion's Mane in the morning and Ashwagandha in the evening. Check with your GP first if you are pregnant, breastfeeding or taking medication.
Is Lion's Mane or Ashwagandha better for stress?: Neither has an authorised UK health claim for stress. Magnesium and Vitamin B6 contribute to normal psychological function.
When should I take Ashwagandha?: Most people take it in the evening. Follow the label on your product.

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Grass & Co. products are food supplements and are not intended to diagnose, treat, cure or prevent any disease. Do not exceed the stated dose. Most products are for adults; CBD is for adults only.